Werner Mohl, MD,PhD, is Professor of Surgery Department of Cardiothoracic Surgery at the University of Vienna. Dr. Mohl has the expertise in the treatment of adult cardiac surgery and a strong background in pediatric cardiac surgery including developmental biology and genetics.

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Recentemente Dr. Mohl entrou em contato com o IPGMRJ, acompanhe abaixo os e-mails enviados:

From: Prof.Dr.Dr.Werner Mohl
To: drstans@uol.com.br
Sent: Friday, March 04, 2011 7:58 AM
Subject: your work on retrograde coronary sinus therapies
 
Dear colleague,
Since you are one of the early pioneers of coronary sinus interventions I am wondering whether you would be interested to write an article for our website: www.coronarysinus.com
I read some of your papers available in the internet and I am fascinated that you as one of the earliest experts in this field could give an important contribution.
Looking forward to your reply
 
ao. Univ. Prof. DDr. Werner Mohl
Professor für Chirurgie
Abteilung für Herz Thoraxchirurgie
Medizinische Universität Wien
Währingergürtel 18-20
1090 Wien

 
From: Prof.Dr.Dr.Werner Mohl
To: 'Prof. Stans Murad'
Sent: Sunday, March 13, 2011 7:16 AM
Subject: WG: Mechanical control of tissue morphogenesis, regeneration and wound healing
 
Dear Professor  !
I really liked your interesting review on retrograde delivery of stem cells and the historic edition on coronary sinus interventions. If I may I would like to include your email into the news section of our Homepage. I wonder however why another important parameter is overlooked. There is strong evidence that epigenetics and not only molecules or cells are heavily involved in regeneration of degenerative structural disease. For instance we work on a special form to treat myocardial ischemia and setting regenerative impulses using mechanotransduction of venous endothelium. PICSO is a clinically feasible form activating coronary venous endothelium and has a lot in common with the present state of the art  of stem cell research. Our focus is more the mechanical force of flowing blood on venous endothelium as well as pulsatile pressure on veins. There is evidence that PICSO by upregulating hemoxygenase has also anti-atherosclerotic potential and we found to the first time also significant long term effects on statistically significant reduction of re-infarction and major adverse cardiac events. Cardiac resident stem cells might also be activated and seem to potentiate positive effects observed.
There seems to be a conservation of regenerative mechanisms normally seen during development. Although our knowledge on the whole perspective is still quite limited, there is a easy available salvage therapy on the horizon. Stem cell effects without stem cell transplantation can be achieved by a simple interventional catheter method without severe ethical restrictions or biohazard normally seen in reprogramming to achieve pluripotency. We think that this opens up a new horizon on potential methods based on our hypothesis “embryonic recall”
I am located in the University of Vienna as cardiac surgeon and if you need more information please let me know. I would be also very interested to hear comments on our hypothesis “embryonic recall”.
 
I enclose some of the recent literature on this topic published by our group. Since you are one of the early pioneers in the field I am very pleased to discuss this important issue with you, since it will be possible that it may set an impulse for a paradigm change in cardiac regeneration. If there would be a chance to visit you or give a presentation in your postgraduate school I would consider to come to your institution as visiting professor!
Best regards from Vienna   
 
ao. Univ. Prof. DDr. Werner Mohl
Professor für Chirurgie
Abteilung für Herz Thoraxchirurgie
Medizinische Universität Wien
Währingergürtel 18-20
1090 Wien
www.meduniwien.ac.at
www.herzchirurg-mohl.at
www.translational-cts.org
www.coronarysinus.com